Bioactive GoHAP nanoparticles and their applications in medical implants technology

Elżbieta Pietrzykowska 1Tadeusz Chudoba 2Jacek Wojnarowicz 2Sylwia Kuśnieruk 3Witold Łojkowski 1,2

1. Instytut Wysokich Ciśnień PAN (IWC), Sokołowska 29/37, Warszawa 01-142, Poland
2. Polish Academy of Sciences, Institute of High Pressure Physics (UNIPRESS), Sokolowska 29/37, Warszawa 01-142, Poland
3. Institute of High Pressure Physics, Polish Academy of Sciences (UNIPRESS), Sokołowska 29/37, Warsaw 01-142, Poland

Abstract

Hydroxyapatite (HAp) is a major inorganic component of human hard tissues, such as bones and teeth, and its content determines their microstructures and physical properties. It is one of few materials that are classed as bioactive, meaning that it will support bone ingrowth and osseointegration when used in orthopaedic, dental and maxillofacial applications.

The Institute of High Pressure Physics of the Polish Academy of Sciences (IHPP) has developed technologies of the nanohydroxyapatite powder synthesis (called GoHAP), obtained by  microwave reactor and the high pressure consolidation technology for ceramic material. Those techniques aim to obtain materials close to the natural structure and mechanical properties of the bone tissues. Obtained GoHAP ideally mimics the natural hydroxyapatite found in human body. The prepared powder has plate and crystalline structure and is characterized by grain size in the range 5-25 nm (it can be controlled); specific surface area is 237m2/g,.  The resorbable powder was investigated according to norm ISO 10993-14.

 

 

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Presentation: Oral at Nano PL 2014, Symposium B, by Elżbieta Pietrzykowska
See On-line Journal of Nano PL 2014

Submitted: 2014-07-10 03:33
Revised:   2014-09-26 15:44