Effect of diisocyanate chemical structure on biocompatibility of segmented polyurethanes

Monika Bil 1,  Joanna Ryszkowska 1,  Edyta Sienkiewicz-Latka 2,  Małgorzata Lewandowska-Szumieł 2

1. Warsaw University of Technology, Faculty of Materials Science and Engineering (InMat), Wołoska 141, Warszawa 02-507, Poland
2. Medical University of Warsaw, Department of Biophysics and Human Physiology, Chałubińskiego 5, Warszawa 02-004, Poland

Abstract

Chemical structure of diisocyanates, poliols and chain extenders affect biocompatibitity of obtained polyurethanes. Hard segments of polyurethanes for biomedical applications are based on both aromatic and aliphatic diisocyanates. The obtained materials have different physico-mechanical properties and their interactions with live tissue.
In this study, polyurethanes with different hard segment diisocyanates (MDI, HMDI) were obtained and their structure, physical properties and biocompatibility were studied. Scanning electron microscopy (SEM), differental scanning calorimetry (DSC), contact angle measurments were used for polyurethane properties characterization.

Project supported by The Polish State Committee for Scientific Reasearch PBZ - KBN-082/T08/2002

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Presentation: poster at E-MRS Fall Meeting 2004, Symposium B, by Monika Bil
See On-line Journal of E-MRS Fall Meeting 2004

Submitted: 2004-04-27 10:12
Revised:   2004-06-07 11:00
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