The term „conjugated linoleic acid” (CLA) refers to a mixture of positional and geometric isomers of octadecadienoic acid with conjugated bonds. Results from experiments in animals indicate that this compound prevents and counteracts chemically induced carcinogenesis, prevents lipid metabolism and atherosclerosis induced via alimentary tract, improves impaired glucose metabolism, exerts protective effects on bone health as well as reduces body fat and increases lean body mass. Detailed mechanism(s) remain to be explained.

In this paper the results of the researches on metabolic effects of CLA are reviewed.

Key words: monounsaturated fatty acids with trans configuration, conjugated linoleic acid, vaccenic acid, metabolic effects of CLA

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