Synthetic osteoinductive biphasic calcium phosphates as scaffolds for bone tissue engineering
|Joost D. de Bruijn , Mirella van den Doel , Clemens Van Blitterswijk , Klaas de Groot , Huipin Yuan|
IsoTis NV, P.O. Box 98, Bilthoven 3720 AB, Netherlands
Porous calcium phosphates have been proposed as bone tissue engineering scaffolds due to their osteoconductive properties and widespread clinical use as synthetic bone graft. Recently, microporous calcium phosphates have been described that are capable of inducing osteogenic differentiation of stem cells and bone formation in ectopic sites. In this study, we investigated such an osteoinductive biphasic calcium phosphate (BCP1200) as a potential bone tissue engineering scaffold and compared this to two non-osteoinductive calcium phosphates (BCP1300 and HA60).
Presentation: invited oral at E-MRS Fall Meeting 2003, Symposium E, by Joost D. de Bruijn
See On-line Journal of E-MRS Fall Meeting 2003
Submitted: 2003-07-01 15:59 Revised: 2009-06-08 12:55