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Nanocrystalline Diamond Coatings - antyallergic barrier onto medical implants

Katarzyna Bąkowicz 1Beata Kręcisz 2Marta Kieć-Świerczyńska 2Piotr Niedzielski 1

1. Technical University of Łódź, Institute of Materials Engineering, Stefanowskiego 1/15, Łódź 90-924, Poland
2. Institute of Occupational Medicine, Teresy 8, Łódź 90-950, Poland

Abstract

Allergy, the main human disorder development of the world civilization.
Many types of allergy can be observed in different pathological situations.
Nowadays, more and more directions of medicine are interested in allergic reactions as a response to changes of homeostasis of a living organism.
Biomedical Engineering as an interdisciplinary science which is mainly connected with the application of medical implants in human organism should to start the examinations which will answer the basic question: Do medical implants protect against allergy in human environment?
There are examples of very strong, dangerous allergic processes after implantation of medical implants without protecting barrier in human body.
The new, pioneer examinations with Nanocrystalline Diamond as a biocompatible and bioactive biomaterial in human body proved these assumptions on the allergic reaction level.
The results of Irritation Reaction (IR) and Allergic Reaction type IV ( hypersensibility delayed reaction; contact eczema) with Diamond Powder Particles on the human skin in lobular tests show the complete biocompatibility with human body; we have not observed any contact allergic reaction to the suspension of Diamond Powder Particles.
The results of examinations with Nanocrystalline Diamond Coatings (NCD) onto metallic samples as a simulation of metallic implants in living organism proved the antiallergic bioactivity of diamond in the contact reaction as a barrier for metals.
The safe future of medical implants in human organism is directly connected with the application of Nanocrystalline Diamond Coatings as an antiallergic barrier to different types of metal implants.

 

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Related papers

Presentation: poster at E-MRS Fall Meeting 2003, Symposium E, by Katarzyna Bąkowicz
See On-line Journal of E-MRS Fall Meeting 2003

Submitted: 2003-05-30 11:27
Revised:   2009-06-08 12:55